articleSLEEPApr 1, 2008BRONZE OA

Cognitive Behavioral Therapy for Insomnia Enhances Depression Outcome in Patients with Comorbid Major Depressive Disorder and Insomnia

RMRachel ManberJDJack D. EdingerJLJenna L. GressMGMelanie G. San Pedro-SalcedoTFTracy F. Kuo

Stanford University · Duke Medical Center

PubMed
Indexed incrossrefpubmed

Abstract

STUDY OBJECTIVE: Insomnia impacts the course of major depressive disorder (MDD), hinders response to treatment, and increases risk for depressive relapse. This study is an initial evaluation of adding cognitive behavioral therapy for insomnia (CBTI) to the antidepressant medication escitalopram (EsCIT) in individuals with both disorders. DESIGN AND SETTING: A randomized, controlled, pilot study in a single academic medical center. PARTICIPANTS: 30 individuals (61% female, mean age 35 +/- 18) with MDD and insomnia. INTERVENTIONS: EsCIT and 7 individual therapy sessions of CBTI or CTRL (quasi-desensitization). MEASUREMENTS AND RESULTS: Depression was assessed with the HRSD17 and the depression portion of the…

Citation impact

870
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FWCI
38.16
Percentile
100%
References
40
Citations per year

Authors

6

Topics & keywords

Topics
Keywords
  • Insomnia
  • Actigraphy
  • Major depressive disorder
  • Cognitive behavioral therapy for insomnia
  • Escitalopram
  • Cognitive behavioral therapy
  • Depression (economics)
  • Psychiatry
UN Sustainable Development Goals
  • Good health and well-being
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