Human body epigenome maps reveal noncanonical DNA methylation variation
Salk Institute for Biological Studies · University of California San Diego · +5 more institutions
Abstract
As part of the Epigenome Roadmap Project, genome-wide maps of DNA methylation and transcriptomes together with genomic DNA sequencing of 18 different primary human tissue types from 4 individuals are presented; analysis reveals widespread differential methylation of CG sites between tissues, and the presence of non-CG methylation in adult tissues. As part of the Epigenome Roadmap project, Joseph Ecker and colleagues provide genome-wide maps of DNA methylation and transcriptomes, in conjunction with genomic DNA sequencing, of 18 different primary human tissue types from four individuals. Analysis of the datasets reveals widespread differential methylation of CG sites between tissues, and methylation at…
Citation impact
- FWCI
- 39.75
- Percentile
- 100%
- References
- 30
Authors
19- MDMatthew D. SchultzCorresponding
Salk Institute for Biological Studies, University of California San Diego
- YHYupeng He
Salk Institute for Biological Studies, University of California San Diego
- JWJohn W. Whitaker
University of California San Diego
- MHManoj Hariharan
Salk Institute for Biological Studies
- EAEran A. Mukamel
Salk Institute for Biological Studies
Topics & keywords
- DNA methylation
- Epigenome
- Biology
- Methylation
- Epigenetics
- RNA-Directed DNA Methylation
- Epigenomics
- Genetics