articleNature Chemical BiologyJun 10, 2015GREEN OA

Catalytic in vivo protein knockdown by small-molecule PROTACs

DPDaniel P. BondesonAMAlina MaresIEIan E. SmithEKEunhwa KoSCSébastien Campos

Yale University · Age UK · +3 more institutions

PubMed
Indexed incrossrefpubmed

Abstract

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1,293
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25.15
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100%
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54
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Authors

29

Topics & keywords

Topics
Keywords
  • Gene knockdown
  • Ubiquitin
  • Ubiquitin ligase
  • Small molecule
  • Target protein
  • Protein degradation
  • Drug discovery
  • RNA interference
UN Sustainable Development Goals
  • Good health and well-being
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