articleHuman Brain MappingMar 22, 2012BRONZE OA

Resting-state networks show dynamic functional connectivity in awake humans and anesthetized macaques

Western University · York University · +1 more institution

PubMed
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Abstract

Characterization of large-scale brain networks using blood-oxygenation-level-dependent functional magnetic resonance imaging is typically based on the assumption of network stationarity across the duration of scan. Recent studies in humans have questioned this assumption by showing that within-network functional connectivity fluctuates on the order of seconds to minutes. Time-varying profiles of resting-state networks (RSNs) may relate to spontaneously shifting, electrophysiological network states and are thus mechanistically of particular importance. However, because these studies acquired data from awake subjects, the fluctuating connectivity could reflect various forms of conscious brain processing such as…

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Authors

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Topics & keywords

Keywords
  • Dynamic functional connectivity
  • Neuroscience
  • Functional magnetic resonance imaging
  • Resting state fMRI
  • Functional connectivity
  • Synchronization (alternating current)
  • Wakefulness
  • Psychology
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