articleMemórias do Instituto Oswaldo CruzJun 4, 2015DIAMOND OA

First report of autochthonous transmission of Zika virus in Brazil

CZCamila ZanlucaVCVanessa Campos Andrade de MeloALAna Luiza Pamplona MosimannGIGlauco Igor Viana dos SantosCNClaudia Nunes Duarte dos Santos

Fundação Oswaldo Cruz · Secretaria da Saúde · +3 more institutions

PubMed
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Abstract

In the early 2015, several cases of patients presenting symptoms of mild fever, rash, conjunctivitis and arthralgia were reported in the northeastern Brazil. Although all patients lived in a dengue endemic area, molecular and serological diagnosis for dengue resulted negative. Chikungunya virus infection was also discarded. Subsequently, Zika virus (ZIKV) was detected by reverse transcription-polymerase chain reaction from the sera of eight patients and the result was confirmed by DNA sequencing. Phylogenetic analysis suggests that the ZIKV identified belongs to the Asian clade. This is the first report of ZIKV infection in Brazil.

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Topics & keywords

Topics
Keywords
  • Chikungunya
  • Zika virus
  • Dengue fever
  • Virology
  • Dengue virus
  • Serology
  • Transmission (telecommunications)
  • Rash
UN Sustainable Development Goals
  • Good health and well-being
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