otherEncyclopedia of BiostatisticsFeb 15, 2005Closed access

M arkov Chain M onte C arlo

MRC Biostatistics Unit

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Abstract

Abstract Markov chain Monte Carlo (MCMC) is a technique for estimating by simulation the expectation of a statistic in a complex model. Successive random selections form a Markov chain, the stationary distribution of which is the target distribution. It is particularly useful for the evaluation of posterior distributions in complex Bayesian models. In the Metropolis–Hastings algorithm, items are selected from an arbitrary “proposal” distribution and are retained or not according to an acceptance rule. The Gibbs sampler is a special case in which the proposal distributions are conditional distributions of single components of a vector parameter. Various special cases and applications are considered.

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Topics & keywords

Keywords
  • Markov chain Monte Carlo
  • Markov chain
  • Gibbs sampling
  • Distribution (mathematics)
  • Bayesian probability
  • Combinatorics
  • Computer science
  • Mathematics
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