Puberty timing associated with diabetes, cardiovascular disease and also diverse health outcomes in men and women: the UK Biobank study
University of Cambridge · Cambridge School · +4 more institutions
Abstract
Early puberty timing is associated with higher risks for type 2 diabetes (T2D) and cardiovascular disease in women and therefore represents a potential target for early preventive interventions. We characterised the range of diseases and other adverse health outcomes associated with early or late puberty timing in men and women in the very large UK Biobank study. Recalled puberty timing and past/current diseases were self-reported by questionnaire. We limited analyses to individuals of White ethnicity (250,037 women; 197,714 men) and to disease outcomes with at least 500 cases (~ 0.2% prevalence) and we applied stringent correction for multiple testing (corrected threshold P
Citation impact
- FWCI
- 50.67
- Percentile
- 100%
- References
- 32
Authors
5- FRFelix R. DayCorresponding
University of Cambridge, Cambridge School, MRC Epidemiology Unit
- CECathy E. Elks
University of Cambridge, Cambridge School, MRC Epidemiology Unit
- AMAnna Murray
University of Exeter, Royal Devon and Exeter Hospital, Exeter Hospital
- KKKen K. Ong
University of Cambridge, Cambridge School, MRC Epidemiology Unit
- JRJohn R. B. Perry
University of Cambridge, Cambridge School, MRC Epidemiology Unit
Topics & keywords
- Medicine
- Menarche
- Disease
- Diabetes mellitus
- Obesity
- Gerontology
- Internal medicine
- Endocrinology
- Good health and well-being