Free radicals, antioxidants in disease and health.
Stanford Medicine · Lucile Packard Children's Hospital
Abstract
Free radicals and oxidants play a dual role as both toxic and beneficial compounds, since they can be either harmful or helpful to the body. They are produced either from normal cell metabolisms in situ or from external sources (pollution, cigarette smoke, radiation, medication). When an overload of free radicals cannot gradually be destroyed, their accumulation in the body generates a phenomenon called oxidative stress. This process plays a major part in the development of chronic and degenerative illness such as cancer, autoimmune disorders, aging, cataract, rheumatoid arthritis, cardiovascular and neurodegenerative diseases. The human body has several mechanisms to counteract oxidative stress by producing…
Citation impact
- FWCI
- 4.52
- Percentile
- 100%
- References
- 51
Authors
3Topics & keywords
- Oxidative stress
- Rheumatoid arthritis
- Antioxidant
- Radical
- Disease
- Medicine
- Catabolism
- Chemistry
- Good health and well-being