reviewBMJFeb 15, 2011HYBRID OA

Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data

CRC Reactive Protein Coronary Heart Disease Genetics Collaboration (CCGC)

University of Cambridge

PubMed
Indexed incrossrefpubmed

Abstract

Objective

To use genetic variants as unconfounded proxies of C reactive protein concentration to study its causal role in coronary heart disease.

Design

Mendelian randomisation meta-analysis of individual participant data from 47 epidemiological studies in 15 countries.

Citation impact

652
total citations
FWCI
36.06
Percentile
100%
References
44
Citations per year

Authors

1
  • CR
    C Reactive Protein Coronary Heart Disease Genetics Collaboration (CCGC)Corresponding

    University of Cambridge

Topics & keywords

Topics
Keywords
  • C-reactive protein
  • Medicine
  • Internal medicine
  • Confidence interval
  • Allele
  • Framingham Risk Score
  • Relative risk
  • Single-nucleotide polymorphism
UN Sustainable Development Goals
  • Good health and well-being
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