reviewNew England Journal of MedicineOct 14, 2009Closed access

Cell Death

Washington University in St. Louis · Walter and Eliza Hall Institute of Medical Research · +1 more institution

PubMed
Indexed incrossrefpubmed

Abstract

This review is a primer on the three main mechanisms of cell death: apoptosis, autophagy-associated cell death, and necrosis. The authors discuss the clinical implications of each of these types of cell death and indicate where advances in our understanding have inspired new forms of therapy.

Citation impact

1,115
total citations
FWCI
43.83
Percentile
100%
References
125
Citations per year

Authors

4

Topics & keywords

Keywords
  • Programmed cell death
  • Autophagy
  • Medicine
  • Apoptosis
  • Necrosis
  • Necroptosis
  • Cause of death
  • Cell
UN Sustainable Development Goals
  • Good health and well-being
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