articleThe Journal of PhysiologyJan 22, 2013GREEN OA

Partially non‐linear stimulation intensity‐dependent effects of direct current stimulation on motor cortex excitability in humans

University of Göttingen · Goethe University Frankfurt

PubMed
Indexed incrossrefpubmed

Abstract

Transcranial direct current stimulation (tDCS) of the human motor cortex at an intensity of 1 mA with an electrode size of 35 cm(2) has been shown to induce shifts of cortical excitability during and after stimulation. These shifts are polarity-specific with cathodal tDCS resulting in a decrease and anodal stimulation in an increase of cortical excitability. In clinical and cognitive studies, stronger stimulation intensities are used frequently, but their physiological effects on cortical excitability have not yet been explored. Therefore, here we aimed to explore the effects of 2 mA tDCS on cortical excitability. We applied 2 mA anodal or cathodal tDCS for 20 min on the left primary motor cortex of 14 healthy…

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Authors

5

Topics & keywords

Keywords
  • Transcranial direct-current stimulation
  • Motor cortex
  • Stimulation
  • Transcranial magnetic stimulation
  • Neuroscience
  • Primary motor cortex
  • Neuroplasticity
  • Psychology
UN Sustainable Development Goals
  • Good health and well-being
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