articleProceedings of the National Academy of SciencesJun 23, 2005GREEN OA

The human brain is intrinsically organized into dynamic, anticorrelated functional networks

MFMichael FoxAZAbraham Z. SnyderJLJustin L. VincentMCMaurizio CorbettaDCDavid C. Van Essen

Washington University in St. Louis

PubMed
Indexed incrossrefpubmed

Abstract

During performance of attention-demanding cognitive tasks, certain regions of the brain routinely increase activity, whereas others routinely decrease activity. In this study, we investigate the extent to which this task-related dichotomy is represented intrinsically in the resting human brain through examination of spontaneous fluctuations in the functional MRI blood oxygen level-dependent signal. We identify two diametrically opposed, widely distributed brain networks on the basis of both spontaneous correlations within each network and anticorrelations between networks. One network consists of regions routinely exhibiting task-related activations and the other of regions routinely exhibiting task-related…

Citation impact

8,820
total citations
FWCI
44.40
Percentile
100%
References
51
Citations per year

Authors

6

Topics & keywords

Topics
Keywords
  • Context (archaeology)
  • Neuroscience
  • Dynamic functional connectivity
  • Task (project management)
  • Human brain
  • Brain function
  • Brain activity and meditation
  • Cognition
No related works found for this paper.

Funding