Hippocampal sharp wave‐ripple: A cognitive biomarker for episodic memory and planning
Indexed incrossrefpubmed
Abstract
Sharp wave ripples (SPW-Rs) represent the most synchronous population pattern in the mammalian brain. Their excitatory output affects a wide area of the cortex and several subcortical nuclei. SPW-Rs occur during "off-line" states of the brain, associated with consummatory behaviors and non-REM sleep, and are influenced by numerous neurotransmitters and neuromodulators. They arise from the excitatory recurrent system of the CA3 region and the SPW-induced excitation brings about a fast network oscillation (ripple) in CA1. The spike content of SPW-Rs is temporally and spatially coordinated by a consortium of interneurons to replay fragments of waking neuronal sequences in a compressed format. SPW-Rs assist in…
Citation impact
1,853
total citations
- FWCI
- 43.90
- Percentile
- 100%
- References
- 904
Citations per year
Authors
1Topics & keywords
Topics
Keywords
- Neuroscience
- Memory consolidation
- Hippocampal formation
- Excitatory postsynaptic potential
- Hippocampus
- Psychology
- Population
- Biological neural network
No related works found for this paper.