Vimentin contributes to epithelial-mesenchymal transition cancer cell mechanics by mediating cytoskeletal organization and focal adhesion maturation

// Ching-Yi Liu 1,2 , Hsi-Hui Lin 2 , Ming-Jer Tang 1,2 and Yang-Kao Wang 1,3,4 1 Institute of Basic Medical Sciences, National Cheng Kung University, Tainan, Taiwan 2 Department of Physiology, National Cheng Kung University, Tainan, Taiwan 3 Department of Cell Biology and Anatomy, National Cheng Kung University, Tainan, Taiwan 4 Center of Neurotrauma and Neuroregeneration, Taipei Medical University, Taipei, Taiwan Correspondence to: Yang-Kao Wang, email: // Ming-Jer Tang, email: // Keywords : vimentin, epithelial-mesenchymal transition (EMT), microtubule, focal adhesions, cell stiffness Received : November 11, 2014 Accepted : March 30, 2015 Published : April 18, 2015 Abstract Modulations of cytoskeletal…

• AS
  Academia Sinica
• MO
  Ministry of Science and Technology, Taiwan

  Award: 2320-B-006
• NC
  National Cheng Kung University