Modes of Action of Herbal Medicines and Plant Secondary Metabolites

Plants produce a wide diversity of secondary metabolites (SM) which serve them as defense compounds against herbivores, and other plants and microbes, but also as signal compounds. In general, SM exhibit a wide array of biological and pharmacological properties. Because of this, some plants or products isolated from them have been and are still used to treat infections, health disorders or diseases. This review provides evidence that many SM have a broad spectrum of bioactivities. They often interact with the main targets in cells, such as proteins, biomembranes or nucleic acids. Whereas some SM appear to have been optimized on a few molecular targets, such as alkaloids on receptors of neurotransmitters,…

• DA
  Deutscher Akademischer Austauschdienst
• DF
  Deutsche Forschungsgemeinschaft
• BF
  Bundesministerium für Bildung und Forschung