reviewJournal of Bone and Joint SurgeryOct 7, 2015GREEN OA

Nontraumatic Osteonecrosis of the Femoral Head: Where Do We Stand Today?

Sinai Hospital · Mayo Clinic · +2 more institutions

PubMed
Indexed incrossrefpubmed

Abstract

➤ Although multiple theories have been proposed, no one pathophysiologic mechanism has been identified as the etiology for the development of osteonecrosis of the femoral head. However, the basic mechanism involves impaired circulation to a specific area that ultimately becomes necrotic.➤ A variety of nonoperative treatment regimens have been evaluated for the treatment of precollapse disease, with varying success. Prospective, multicenter, randomized trials are needed to evaluate the efficacy of these regimens in altering the natural history of the disease.➤ Joint-preserving procedures are indicated in the treatment of precollapse disease, with several studies showing successful outcomes at mid-term and…

Citation impact

593
total citations
FWCI
23.37
Percentile
100%
References
471
Citations per year

Authors

5

Topics & keywords

Keywords
  • Femoral head
  • Medicine
  • Etiology
  • Surgery
  • Disease
  • Arthroplasty
  • Clinical trial
  • Natural history
UN Sustainable Development Goals
  • Good health and well-being
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