articleProceedings of the National Academy of SciencesAug 31, 2015BRONZE OA

Dynamic reconfiguration of frontal brain networks during executive cognition in humans

Heidelberg University · University Hospital Heidelberg · +3 more institutions

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Abstract

The brain is an inherently dynamic system, and executive cognition requires dynamically reconfiguring, highly evolving networks of brain regions that interact in complex and transient communication patterns. However, a precise characterization of these reconfiguration processes during cognitive function in humans remains elusive. Here, we use a series of techniques developed in the field of "dynamic network neuroscience" to investigate the dynamics of functional brain networks in 344 healthy subjects during a working-memory challenge (the "n-back" task). In contrast to a control condition, in which dynamic changes in cortical networks were spread evenly across systems, the effortful working-memory condition…

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