article·Nature Biotechnology·Nov 2, 2015BRONZE OA

Broadening the targeting range of Staphylococcus aureus CRISPR-Cas9 by modifying PAM recognition

BPBenjamin P. KleinstiverCorresponding authorMSMichelle S. PrewSQShengdar Q. TsaiNTNathalie T. NguyenVVVed V. Topkar

Center for Cancer Research · Massachusetts General Hospital · +2 more institutions

PubMed
Indexed incrossrefpubmed

Abstract

No abstract available for this paper.

Citation impact

628
total citations
FWCI
30.11
Percentile
100%
References
38
Citations per year

Authors

7
  • BP
    Benjamin P. KleinstiverCorresponding

    Center for Cancer Research, Massachusetts General Hospital, Harvard University

  • MS
    Michelle S. Prew

    Center for Cancer Research, Massachusetts General Hospital

  • SQ
    Shengdar Q. Tsai

    Center for Cancer Research, Harvard University, Massachusetts General Hospital

  • NT
    Nathalie T. Nguyen

    Massachusetts General Hospital, Center for Cancer Research

  • VV
    Ved V. Topkar

    Center for Cancer Research, Massachusetts General Hospital

Topics & keywords

Topics
  • Primary topicCRISPR and Genetic Engineering100%
  • RNA and protein synthesis mechanisms99%
  • RNA regulation and disease99%
Keywords
  • Cas9
  • CRISPR
  • Guide RNA
  • Biology
  • Genome editing
  • Computational biology
  • Genome
  • DNA
No related works found for this paper.

Funding

  • NI
    National Institutes of Health
    Awards: GM105378, DP1 GM105378, NIH R01
  • NS
    Natural Sciences and Engineering Research Council of Canada