articleNucleic Acids ResearchJan 1, 2003BRONZE OA

CDD: a curated Entrez database of conserved domain alignments

AMAron Marchler‐Bauer

National Center for Biotechnology Information · National Institutes of Health

PubMed
Indexed incrossrefdoajpubmed

Abstract

The Conserved Domain Database (CDD) is now indexed as a separate database within the Entrez system and linked to other Entrez databases such as MEDLINE(R). This allows users to search for domain types by name, for example, or to view the domain architecture of any protein in Entrez's sequence database. CDD can be accessed on the WorldWideWeb at http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=cdd. Users may also employ the CD-Search service to identify conserved domains in new sequences, at http://www.ncbi.nlm.nih.gov/Structure/cdd/wrpsb.cgi. CD-Search results, and pre-computed links from Entrez's protein database, are calculated using the RPS-BLAST algorithm and Position Specific Score Matrices (PSSMs)…

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Topics & keywords

Topics
Keywords
  • Biology
  • Domain (mathematical analysis)
  • Conserved sequence
  • Protein domain
  • Sequence alignment
  • Sequence database
  • Multiple sequence alignment
  • Database
UN Sustainable Development Goals
  • Life in Land
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