Impact of maternal intrapartum antibiotics, method of birth and breastfeeding on gut microbiota during the first year of life: a prospective cohort study

Azad, Meghan B.; Konya, Theodore; Persaud, RR; Guttman, DS; Chari, RS; Field, Catherine J.; Sears, MR; Mandhane, PJ; Turvey, SE; Subbarao, Padmaja; Becker, A.B.; Scott, James A.; Kozyrskyj, Anita L.; Investigators, the CHILD Study

doi:10.1111/1471-0528.13601

articleBJOG An International Journal of Obstetrics & GynaecologySep 28, 2015Closed access

Impact of maternal intrapartum antibiotics, method of birth and breastfeeding on gut microbiota during the first year of life: a prospective cohort study

MBMeghan B. Azad TKTheodore Konya RPRR Persaud DGDS Guttman RCRS Chari

University of Alberta · Children's Hospital Research Institute of Manitoba · +9 more institutions

PubMed

Indexed incrossrefpubmed

Abstract

Objective

Dysbiosis of the infant gut microbiota may have long-term health consequences. This study aimed to determine the impact of maternal intrapartum antibiotic prophylaxis (IAP) on infant gut microbiota, and to explore whether breastfeeding modifies these effects.

Design

Prospective pregnancy cohort of Canadian infants born in 2010-2012: the Canadian Healthy Infant Longitudinal Development (CHILD) Study.

Citation impact

612

total citations

FWCI: 22.89
Percentile: 100%
References: 43

Citations per year

Authors

14

Topics & keywords

Topics

Keywords

Breastfeeding
Medicine
Gut flora
Dysbiosis
Prospective cohort study
Pregnancy
Cohort study
Caesarean section

UN Sustainable Development Goals

Good health and well-being

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