Injectable, Cellular-Scale Optoelectronics with Applications for Wireless Optogenetics

Successful integration of advanced semiconductor devices with biological systems will accelerate basic scientific discoveries and their translation into clinical technologies. In neuroscience generally, and in optogenetics in particular, the ability to insert light sources, detectors, sensors, and other components into precise locations of the deep brain yields versatile and important capabilities. Here, we introduce an injectable class of cellular-scale optoelectronics that offers such features, with examples of unmatched operational modes in optogenetics, including completely wireless and programmed complex behavioral control over freely moving animals. The ability of these ultrathin, mechanically compliant,…

• UD
  U.S. Department of Energy

  Awards: FG02-07ER46453, DE-FG02-07ER46471, DE-FG02-07ER46453, DE-FG02-, DE-FG02, FG02-07ER46471
• HC
  Hope Center for Neurological Disorders
• NI
  National Institutes of Health

  Award: R01NS081707
• UO
  University of Illinois at Urbana-Champaign
• MC
  McDonnell Center for Systems Neuroscience
• NI
  National Institute on Drug Abuse

  Award: R00DA025182
• NI
  National Institute of Neurological Disorders and Stroke

  Award: R01NS081707
• DO
  Division of Materials Research
• CF
  Common Fund