articleCancerFeb 2, 2009BRONZE OA

Role of surgical outcome as prognostic factor in advanced epithelial ovarian cancer: A combined exploratory analysis of 3 prospectively randomized phase 3 multicenter trials

Helios Dr. Horst Schmidt Kliniken Wiesbaden · Arbeitsgemeinschaft Gynäkologische Onkologie Studiengruppe · +4 more institutions

PubMed
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Abstract

Background

Primary surgery followed by platinum-taxane based chemotherapy has been the standard therapy in advanced ovarian cancer. However, the prognostic role of complete and so-called optimal and suboptimal debulking and its interaction with biological factors has not been not fully defined.

Methods

Exploratory analysis was conducted of 3 prospective randomized trials (AGO-OVAR 3, 5, and 7) investigating platinum-taxane based chemotherapy regimens in advanced ovarian cancer conducted between 1995 and 2002.

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