article·Nature·Mar 29, 2009Closed access

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

TSToshiro SatoCorresponding authorRGRobert G.J. VriesHJHugo J.G. SnippertMVMarc van de WeteringNBNick Barker

Hubrecht Institute for Developmental Biology and Stem Cell Research · University Medical Center Utrecht · +2 more institutions

PubMed
Indexed incrossrefpubmed

Abstract

No abstract available for this paper.

Citation impact

7,102
total citations
FWCI
63.10
Percentile
100%
References
33
Citations per year

Authors

11
  • TS
    Toshiro SatoCorresponding

    Hubrecht Institute for Developmental Biology and Stem Cell Research, University Medical Center Utrecht

  • RG
    Robert G.J. Vries

    University Medical Center Utrecht, Hubrecht Institute for Developmental Biology and Stem Cell Research

  • HJ
    Hugo J.G. Snippert

    University Medical Center Utrecht, Hubrecht Institute for Developmental Biology and Stem Cell Research

  • MV
    Marc van de Wetering

    University Medical Center Utrecht, Hubrecht Institute for Developmental Biology and Stem Cell Research

  • NB
    Nick Barker

    Hubrecht Institute for Developmental Biology and Stem Cell Research, University Medical Center Utrecht

Topics & keywords

Topics
  • Primary topicCancer Cells and Metastasis100%
  • Liver physiology and pathology98%
  • Pancreatic function and diabetes96%
Keywords
  • LGR5
  • Stem cell
  • Crypt
  • Organoid
  • Biology
  • Cell biology
  • Epithelium
  • Mesenchymal stem cell
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