Outcomes after Transplantation of Cord Blood or Bone Marrow from Unrelated Donors in Adults with Leukemia
Medical College of Wisconsin · New York Blood Center · +4 more institutions
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Abstract
Background
Data regarding the outcome of cord-blood transplantation in adults are scant, despite the fact that these grafts are increasingly used in adults.
Methods
We compared the outcomes of the transplantation of hematopoietic stem cells from unrelated donors in adults with leukemia who had received cord blood that was mismatched for one HLA antigen (34 patients) or two antigens (116 patients), bone marrow that had one HLA mismatch (83 patients), and HLA-matched bone marrow (367 patients). We used Cox proportional-hazards models to analyze the data.
Citation impact
1,056
total citations
- FWCI
- 32.90
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- 100%
- References
- 33
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Authors
14Topics & keywords
Topics
Keywords
- Medicine
- Cord blood
- Bone marrow
- Transplantation
- Leukemia
- Human leukocyte antigen
- Internal medicine
- Acute leukemia
UN Sustainable Development Goals
- Good health and well-being
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