articleCirculationAug 14, 2007BRONZE OA

Prognostic Value of Very Low Plasma Concentrations of Troponin T in Patients With Stable Chronic Heart Failure

New York Medical College · Mario Negri Institute for Pharmacological Research · +6 more institutions

PubMed
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Abstract

BACKGROUND: Circulating cardiac troponin T, a marker of cardiomyocyte injury, predicts adverse outcome in patients with heart failure (HF) but is detectable in only a small fraction of those with chronic stable HF. We assessed the prognostic value of circulating cardiac troponin T in patients with stable chronic HF with a traditional (cTnT) and a new precommercial highly sensitive assay (hsTnT). METHODS AND RESULTS: Plasma troponin T was measured in 4053 patients with chronic HF enrolled in the Valsartan Heart Failure Trial (Val-HeFT). Troponin T was detectable in 10.4% of the population with the cTnT assay (detection limit

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Authors

12

Topics & keywords

Keywords
  • Medicine
  • Heart failure
  • Cardiology
  • Internal medicine
  • Troponin
  • Troponin I
  • Myocardial infarction
UN Sustainable Development Goals
  • Peace, Justice and strong institutions
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