Protein-to-protein interactions

Studying proteins and their structures has an important role for understanding protein functionalities. Recently, due to important results obtained with proteomics, a great interest has been given to interactomics , that is, the study of protein-to-protein interactions, called PPI, or more generally, interactions among macromolecules, particularly within cells. Interactomics means studying, modeling, storing, and retrieving protein-to-protein interactions as well as algorithms for manipulating, simulating, and predicting interactions. PPI data can be obtained from biological experiments studying interactions. Modeling and storing PPIs can be realized by using graph theory and graph data management, thus graph…