reviewMedical & Biological Engineering & ComputingNov 1, 2008HYBRID OA

An image-based modeling framework for patient-specific computational hemodynamics

Mario Negri Institute for Pharmacological Research · University of Bergamo · +1 more institution

PubMed
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Abstract

We present a modeling framework designed for patient-specific computational hemodynamics to be performed in the context of large-scale studies. The framework takes advantage of the integration of image processing, geometric analysis and mesh generation techniques, with an accent on full automation and high-level interaction. Image segmentation is performed using implicit deformable models taking advantage of a novel approach for selective initialization of vascular branches, as well as of a strategy for the segmentation of small vessels. A robust definition of centerlines provides objective geometric criteria for the automation of surface editing and mesh generation. The framework is available as part of an…

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