Vertebrate MicroRNA Genes

Lim, Lee P.; Glasner, Margaret E.; Yekta, Soraya; Burge, Christopher B.; Bartel, David P.

doi:10.1126/science.1080372

articleScienceMar 6, 2003Closed access

Vertebrate MicroRNA Genes

LPLee P. Lim MEMargaret E. Glasner SYSoraya Yekta CBChristopher B. Burge DPDavid P. Bartel

Whitehead Institute for Biomedical Research · Massachusetts Institute of Technology

PubMed

Indexed incrossrefpubmed

Abstract

MicroRNAs (miRNAs) are an abundant class of ∼22-nucleotide (nt) noncoding RNAs, some of which are known to control the expression of other genes at the posttranscriptional level ([1–4][1]). We developed a computational procedure (MiRscan) to identify miRNA genes ([5][2]) and apply it here to

Citation impact

1,216

total citations

FWCI: 39.53
Percentile: 100%
References: 5

Citations per year

Authors

LP
Lee P. LimCorresponding
Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology
ME
Margaret E. GlasnerCorresponding
Massachusetts Institute of Technology, Whitehead Institute for Biomedical Research
SY
Soraya YektaCorresponding
Massachusetts Institute of Technology, Whitehead Institute for Biomedical Research
CB
Christopher B. BurgeCorresponding
Massachusetts Institute of Technology
DP
David P. BartelCorresponding
Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology

Topics & keywords

Topics

MicroRNA in disease regulation100%
Cancer-related molecular mechanisms research100%
RNA modifications and cancer100%

Keywords

Vertebrate
microRNA
Gene
Biology
Evolutionary biology
Genetics
Computational biology

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