Quantification of Plasma Epstein–Barr Virus DNA in Patients with Advanced Nasopharyngeal Carcinoma
Taichung Veterans General Hospital · National Cheng Kung University Hospital · +2 more institutions
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Abstract
Background
We investigated the clinical significance of plasma concentrations of Epstein-Barr virus (EBV) DNA in patients with advanced nasopharyngeal carcinoma.
Methods
Ninety-nine patients with biopsy-proven stage III or IV nasopharyngeal carcinoma and no evidence of metastasis (M0) received 10 weekly chemotherapy treatments followed by radiotherapy. Plasma samples from the patients were subjected to a real-time quantitative polymerase-chain-reaction assay. EBV genotypes of paired samples from plasma and primary tumor were compared.
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921
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Authors
7Topics & keywords
Topics
Keywords
- Nasopharyngeal carcinoma
- Medicine
- Virus
- Gastroenterology
- Internal medicine
- Radiation therapy
- Liter
- Stage (stratigraphy)
UN Sustainable Development Goals
- Good health and well-being
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