Raman spectroscopy for medical diagnostics — From in-vitro biofluid assays to in-vivo cancer detection
University of Nottingham · University of Exeter · +1 more institution
Abstract
Raman spectroscopy is an optical technique based on inelastic scattering of light by vibrating molecules and can provide chemical fingerprints of cells, tissues or biofluids. The high chemical specificity, minimal or lack of sample preparation and the ability to use advanced optical technologies in the visible or near-infrared spectral range (lasers, microscopes, fibre-optics) have recently led to an increase in medical diagnostic applications of Raman spectroscopy. The key hypothesis underpinning this field is that molecular changes in cells, tissues or biofluids, that are either the cause or the effect of diseases, can be detected and quantified by Raman spectroscopy. Furthermore, multivariate calibration…
Citation impact
- FWCI
- 79.29
- Percentile
- 100%
- References
- 136
Authors
4Topics & keywords
- Raman spectroscopy
- Spectroscopy
- Laser
- Raman scattering
- Materials science
- Optics
- Analytical Chemistry (journal)
- Nanotechnology