MicroRNA and cancer

With the advent of next generation sequencing techniques a previously unknown world of non-coding RNA molecules have been discovered. Non-coding RNA transcripts likely outnumber the group of protein coding sequences and hold promise of many new discoveries and mechanistic explanations for essential biological phenomena and pathologies. The best characterized non-coding RNA family consists in humans of about 1400 microRNAs for which abundant evidence have demonstrated fundamental importance in normal development, differentiation, growth control and in human diseases such as cancer. In this review, we summarize the current knowledge and concepts concerning the involvement of microRNAs in cancer, which have…

• KB
  Kræftens Bekæmpelse
• H
  Højteknologifonden
• NR
  National Research Foundation
• DG
  Danmarks Grundforskningsfond
• L
  Lundbeckfonden
• NN
  Novo Nordisk
• NN
  Novo Nordisk Fonden
• HL
  H. Lundbeck A/S