reviewBMJFeb 22, 2011HYBRID OA

Effect of alcohol consumption on biological markers associated with risk of coronary heart disease: systematic review and meta-analysis of interventional studies

Institute of Population and Public Health · University of Calgary · +4 more institutions

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Abstract

Objective

To systematically review interventional studies of the effects of alcohol consumption on 21 biological markers associated with risk of coronary heart disease in adults without known cardiovascular disease.

Design

Systematic review and meta-analysis. DATA SOURCES: Medline (1950 to October 2009) and Embase (1980 to October 2009) without limits. STUDY SELECTION: Two reviewers independently selected studies that examined adults without known cardiovascular disease and that compared fasting levels of specific biological markers associated with coronary heart disease after alcohol use with those after a period of no alcohol use (controls). 4690 articles were screened for eligibility, the full texts of 124 studies reviewed, and 63 relevant articles selected.

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