Ligand-Independent HER2/HER3/PI3K Complex Is Disrupted by Trastuzumab and Is Effectively Inhibited by the PI3K Inhibitor GDC-0941
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Abstract
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Citation impact
830
total citations
- FWCI
- 31.09
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- 100%
- References
- 43
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Authors
8Topics & keywords
Topics
Keywords
- Trastuzumab
- PI3K/AKT/mTOR pathway
- Ligand (biochemistry)
- Cancer research
- Discovery and development of mTOR inhibitors
- Chemistry
- Pharmacology
- Cell biology
UN Sustainable Development Goals
- Good health and well-being
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