Liver stiffness measurement predicts severe portal hypertension in patients with HCV‐related cirrhosis†‡

UNLABELLED: Measurement of hepatic venous pressure gradient (HVPG) is a standard method for the assessment of portal pressure and correlates with the occurrence of its complications. Liver stiffness measurement (LSM) has been proposed as a noninvasive technique for the prediction of the complications of cirrhosis. In this study, we evaluated the ability of LSM to predict severe portal hypertension compared with that of HVPG in 61 consecutive patients with HCV-related chronic liver disease. A strong relationship between LSM and HVPG measurements was found in the overall population (r=0.81, Por=10 mm Hg (r2=0.35, Por=12 mm Hg (r2=0.17, P=0.02). The AUROC for the prediction of HVPG>or=10 and >or=12 mm Hg were…

• MD
  Ministero dell’Istruzione, dell’Università e della Ricerca
• UD
  Università degli Studi di Firenze