Presenting Vancomycin on Nanoparticles to Enhance Antimicrobial Activities
Hong Kong University of Science and Technology · University of Hong Kong
Abstract
Here we report the synthesis of vancomycin (Van)-capped Au nanoparticles (Au@Van) and their enhanced in vitro antibacterial activities. Au@Van presumably acts as a rigid polyvalent inhibitor of vancomycin-resistant enterococci (VRE). It also has unexpected activity against an E. coli strain. Our results suggest that gold nanoparticles may serve as a useful model system to explore multi/polyvalent interactions of ligand−receptor pairs.
Citation impact
- FWCI
- 3.34
- Percentile
- 100%
- References
- 13
Authors
5- HGHongwei GuCorresponding
Hong Kong University of Science and Technology, University of Hong Kong
- PHPak‐Leung Ho
University of Hong Kong, Hong Kong University of Science and Technology
- ETEdmond Tong
University of Hong Kong, Hong Kong University of Science and Technology
- LWLing Wang
Hong Kong University of Science and Technology, University of Hong Kong
- BXBing Xu
Hong Kong University of Science and Technology, University of Hong Kong
Topics & keywords
- Vancomycin
- Nanoparticle
- Antimicrobial
- Colloidal gold
- Ligand (biochemistry)
- In vitro
- Chemistry
- Strain (injury)