articleNucleic Acids ResearchJul 25, 2014GOLD OA

The multiMiR R package and database: integration of microRNA–target interactions along with their disease and drug associations

YRYuanbin RuKKKaterina KechrisBTBoris TabakoffPHPaula HoffmanRARichard A. Radcliffe

University of Colorado Denver · Colorado School of Public Health · +4 more institutions

PubMed
Indexed incrossrefdoajpubmed

Abstract

MicroRNAs (miRNAs) regulate expression by promoting degradation or repressing translation of target transcripts. miRNA target sites have been catalogued in databases based on experimental validation and computational prediction using various algorithms. Several online resources provide collections of multiple databases but need to be imported into other software, such as R, for processing, tabulation, graphing and computation. Currently available miRNA target site packages in R are limited in the number of databases, types of databases and flexibility. We present multiMiR, a new miRNA-target interaction R package and database, which includes several novel features not available in existing R packages: (i)…

Citation impact

762
total citations
FWCI
4.02
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100%
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48
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Authors

11

Topics & keywords

Topics
Keywords
  • Annotation
  • Database
  • Biology
  • microRNA
  • Computational biology
  • Software
  • Computer science
  • Bioinformatics
UN Sustainable Development Goals
  • Good health and well-being
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