Dynamic functional reorganization of the motor execution network after stroke

Numerous studies argue that cortical reorganization may contribute to the restoration of motor function following stroke. However, the evolution of changes during the post-stroke reorganization has been little studied. This study sought to identify dynamic changes in the functional organization, particularly topological characteristics, of the motor execution network during the stroke recovery process. Ten patients (nine male and one female) with subcortical infarctions were assessed by neurological examination and scanned with resting-state functional magnetic resonance imaging across five consecutive time points in a single year. The motor execution network of each subject was constructed using a functional…

• NN
  National Natural Science Foundation of China

  Awards: 2003CB716101, 30970773, 30670601
• PF
  Program for New Century Excellent Talents in University

  Award: NCET-07-0568