reviewPhysics in Medicine and BiologyOct 16, 2012Closed access

A review of partial volume correction techniques for emission tomography and their applications in neurology, cardiology and oncology

University College London · Centre National de la Recherche Scientifique · +1 more institution

PubMed
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Abstract

Accurate quantification in PET and SPECT requires correction for a number of physical factors, such as photon attenuation, Compton scattering and random coincidences (in PET). Another factor affecting quantification is the limited spatial resolution. While considerable effort has gone into development of routine correction techniques for the former factors, less attention has been paid to the latter. Spatial resolution-related effects, referred to as 'partial volume effects' (PVEs), depend not only on the characteristics of the imaging system but also on the object and activity distribution. Spatial and/or temporal variations in PVE can often be confounding factors. Partial volume correction (PVC) could in…

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