Triplets of Spikes in a Model of Spike Timing-Dependent Plasticity

Classical experiments on spike timing-dependent plasticity (STDP) use a protocol based on pairs of presynaptic and postsynaptic spikes repeated at a given frequency to induce synaptic potentiation or depression. Therefore, standard STDP models have expressed the weight change as a function of pairs of presynaptic and postsynaptic spike. Unfortunately, those paired-based STDP models cannot account for the dependence on the repetition frequency of the pairs of spike. Moreover, those STDP models cannot reproduce recent triplet and quadruplet experiments. Here, we examine a triplet rule (i.e., a rule which considers sets of three spikes, i.e., two pre and one post or one pre and two post) and compare it to…

• NS
  National Science Foundation

  Award: 200020
• SN
  Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung

  Awards: 108097, 200020