Management of Neuropsychiatric Symptoms of Dementia in Clinical Settings: Recommendations from a Multidisciplinary Expert Panel
University of Michigan · VA Ann Arbor Healthcare System · +6 more institutions
Abstract
Noncognitive neuropsychiatric symptoms (NPS) of dementia (aggression, agitation, depression, anxiety, delusions, hallucinations, apathy, disinhibition) affect individuals with dementia nearly universally across dementia stages and etiologies. NPS are associated with poor outcomes for individuals with dementia and caregivers, including excess morbidity and mortality, greater healthcare use, and earlier nursing home placement, as well as caregiver stress, depression, and difficulty with employment. Although the Food and Drug Administration has not approved pharmacotherapy for NPS, psychotropic medications are frequently used to manage these symptoms, but in the few cases of proven pharmacological efficacy,…
Citation impact
- FWCI
- 28.23
- Percentile
- 100%
- References
- 40
Authors
4- HCHelen C. KalesCorresponding
University of Michigan, VA Ann Arbor Healthcare System, Geriatric Research Education and Clinical Center, VA Center for Clinical Management Research
- LNLaura N. Gitlin
Johns Hopkins University, Johns Hopkins Medicine, Johns Hopkins Bayview Medical Center
- CGConstantine G. Lyketsos
Johns Hopkins University, Johns Hopkins Bayview Medical Center, Alzheimer’s Disease Neuroimaging Initiative
- TDthe Detroit Expert Panel on the Assessment and Management of the Neuropsychiatric Symptoms of Dementia
Topics & keywords
- Medicine
- Dementia
- Apathy
- Context (archaeology)
- Psychiatry
- Depression (economics)
- Anxiety
- Multidisciplinary approach