articleNature BiotechnologyApr 11, 2004HYBRID OA

The genome sequence of the anaerobic, sulfate-reducing bacterium Desulfovibrio vulgaris Hildenborough

Human Genome Sciences (United States) · University of Calgary · +6 more institutions

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Abstract

Desulfovibrio vulgaris Hildenborough is a model organism for studying the energy metabolism of sulfate-reducing bacteria (SRB) and for understanding the economic impacts of SRB, including biocorrosion of metal infrastructure and bioremediation of toxic metal ions. The 3,570,858 base pair (bp) genome sequence reveals a network of novel c-type cytochromes, connecting multiple periplasmic hydrogenases and formate dehydrogenases, as a key feature of its energy metabolism. The relative arrangement of genes encoding enzymes for energy transduction, together with inferred cellular location of the enzymes, provides a basis for proposing an expansion to the 'hydrogen-cycling' model for increasing energy efficiency in…

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Authors

35

Topics & keywords

Keywords
  • Desulfovibrio vulgaris
  • Desulfovibrio
  • Bacteria
  • Hydrogenase
  • Biology
  • Sulfate-reducing bacteria
  • Periplasmic space
  • Bioremediation
UN Sustainable Development Goals
  • Affordable and clean energy
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