Global epidemiology of hepatitis C virus infection: New estimates of age-specific antibody to HCV seroprevalence

UNLABELLED: In efforts to inform public health decision makers, the Global Burden of Diseases, Injuries, and Risk Factors 2010 (GBD2010) Study aims to estimate the burden of disease using available parameters. This study was conducted to collect and analyze available prevalence data to be used for estimating the hepatitis C virus (HCV) burden of disease. In this systematic review, antibody to HCV (anti-HCV) seroprevalence data from 232 articles were pooled to estimate age-specific seroprevalence curves in 1990 and 2005, and to produce age-standardized prevalence estimates for each of 21 GBD regions using a model-based meta-analysis. This review finds that globally the prevalence and number of people with…

• UD
  U.S. Department of Energy
• WH
  World Health Organization
• UO
  University of Washington
• IF
  Institute for Health Metrics and Evaluation
• CF
  Centers for Disease Control and Prevention
• OR
  Oak Ridge Institute for Science and Education