An Engineered Microbial Platform for Direct Biofuel Production from Brown Macroalgae
Fundación Chile · Clínica Las Condes · +1 more institution
Abstract
Prospecting macroalgae (seaweeds) as feedstocks for bioconversion into biofuels and commodity chemical compounds is limited primarily by the availability of tractable microorganisms that can metabolize alginate polysaccharides. Here, we present the discovery of a 36-kilo-base pair DNA fragment from Vibrio splendidus encoding enzymes for alginate transport and metabolism. The genomic integration of this ensemble, together with an engineered system for extracellular alginate depolymerization, generated a microbial platform that can simultaneously degrade, uptake, and metabolize alginate. When further engineered for ethanol synthesis, this platform enables bioethanol production directly from macroalgae via a…
Citation impact
- FWCI
- 30.46
- Percentile
- 100%
- References
- 45
Authors
14Topics & keywords
- Bioconversion
- Biofuel
- Chemistry
- Biomass (ecology)
- Microorganism
- Bioenergy
- Commodity chemicals
- Yield (engineering)
- Life below water