Cardiovascular Events and Intensity of Treatment in Polycythemia Vera
Mario Negri Sud Foundation · Azienda Ospedaliero Universitaria Ospedali Riuniti · +27 more institutions
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Abstract
Background
Current treatment recommendations for patients with polycythemia vera call for maintaining a hematocrit of less than 45%, but this therapeutic strategy has not been tested in a randomized clinical trial.
Methods
We randomly assigned 365 adults with JAK2-positive polycythemia vera who were being treated with phlebotomy, hydroxyurea, or both to receive either more intensive treatment (target hematocrit,
Citation impact
812
total citations
- FWCI
- 22.98
- Percentile
- 100%
- References
- 21
Citations per year
Authors
32Topics & keywords
Topics
Keywords
- Medicine
- Polycythemia vera
- Intensity (physics)
- Internal medicine
- Cardiology
- Intensive care medicine
UN Sustainable Development Goals
- Good health and well-being
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