Towards a theory of biological robustness

Mol Syst Biol. 3: 137 Robustness is one of the fundamental characteristics of biological systems. Numerous reports have been published on how robustness is involved in various biological processes and on mechanisms that give rise to robustness in living systems (Savageau, 1985a, 1985b, 1998; Barkai and Leibler, 1997; Alon et al , 1999; von Dassow et al , 2000; Bhalla and Iyengar, 2001; Csete and Doyle, 2002, 2004; Kitano et al , 2004, 2004a, 2004b; Stelling et al , 2004; Kitano and Oda, 2006; Kitano, 2007a). With increasing interest in systems biology, properties at the system level such as robustness have attracted serious scientific research. Nevertheless, a mathematical foundation that provides a unified…

• JS
  Japan Science and Technology Agency
• ER
  Exploratory Research for Advanced Technology