Soluble CD40 Ligand in Acute Coronary Syndromes
Goethe University Frankfurt · Kerckhoff Klinik · +1 more institution
Indexed incrossrefpubmed
Abstract
Background
CD40 ligand is expressed on platelets and released from them on activation. We investigated the predictive value of soluble CD40 ligand as a marker for clinical outcome and the therapeutic effect of glycoprotein IIb/IIIa receptor inhibition in patients with acute coronary syndromes.
Methods
Serum levels of soluble CD40 ligand were measured in 1088 patients with acute coronary syndromes who had previously been enrolled in a randomized trial comparing abciximab with placebo before coronary angioplasty and in 626 patients with acute chest pain.
Citation impact
826
total citations
- FWCI
- 25.62
- Percentile
- 100%
- References
- 49
Citations per year
Authors
7Topics & keywords
Topics
Keywords
- Medicine
- Hazard ratio
- Myocardial infarction
- Abciximab
- Internal medicine
- Confidence interval
- Placebo
- Chest pain
UN Sustainable Development Goals
- Good health and well-being
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