Prostate cancer-derived urine exosomes: a novel approach to biomarkers for prostate cancer
Umeå University · Massachusetts General Hospital · +1 more institution
Indexed incrossrefpubmed
Abstract
Herein, we describe a novel approach in the search for prostate cancer biomarkers, which relies on the transcriptome within tumour exosomes. As a proof-of-concept, we show the presence of two known prostate cancer biomarkers, PCA-3 and TMPRSS2:ERG the in exosomes isolated from urine of patients, showing the potential for diagnosis and monitoring cancer patients status.
Citation impact
780
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- FWCI
- 11.63
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- 100%
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Authors
7Topics & keywords
Topics
Keywords
- Prostate cancer
- Microvesicles
- Cancer
- Medicine
- Prostate
- PCA3
- Biomarker
- Biomarker discovery
UN Sustainable Development Goals
- Good health and well-being
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