reviewAdvanced MaterialsJan 10, 2015HYBRID OA

Natural‐Based Nanocomposites for Bone Tissue Engineering and Regenerative Medicine: A Review

University of Minho

PubMed
Indexed incrossrefpubmed

Abstract

Tissue engineering and regenerative medicine has been providing exciting technologies for the development of functional substitutes aimed to repair and regenerate damaged tissues and organs. Inspired by the hierarchical nature of bone, nanostructured biomaterials are gaining a singular attention for tissue engineering, owing their ability to promote cell adhesion and proliferation, and hence new bone growth, compared with conventional microsized materials. Of particular interest are nanocomposites involving biopolymeric matrices and bioactive nanosized fillers. Biodegradability, high mechanical strength, and osteointegration and formation of ligamentous tissue are properties required for such materials.…

Citation impact

931
total citations
FWCI
43.82
Percentile
100%
References
316
Citations per year

Authors

3

Topics & keywords

Keywords
  • Materials science
  • Nanocomposite
  • Biocompatibility
  • Tissue engineering
  • Regenerative medicine
  • Self-healing hydrogels
  • Nanotechnology
  • Bone tissue
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