Infrared light excites cells by changing their electrical capacitance
University of Chicago · Northwestern University
Abstract
Optical stimulation has enabled important advances in the study of brain function and other biological processes, and holds promise for medical applications ranging from hearing restoration to cardiac pace making. In particular, pulsed laser stimulation using infrared wavelengths >1.5 μm has therapeutic potential based on its ability to directly stimulate nerves and muscles without any genetic or chemical pre-treatment. However, the mechanism of infrared stimulation has been a mystery, hindering its path to the clinic. Here we show that infrared light excites cells through a novel, highly general electrostatic mechanism. Infrared pulses are absorbed by water, producing a rapid local increase in temperature.…
Citation impact
- FWCI
- 15.11
- Percentile
- 100%
- References
- 32
Authors
5Topics & keywords
- Infrared
- Stimulation
- Depolarization
- Capacitance
- Mechanism (biology)
- Materials science
- Optoelectronics
- Biophysics
- Clean water and sanitation