reviewACS NanoJul 27, 2012GREEN OA

Electrochemical Immunosensors for Detection of Cancer Protein Biomarkers

National Institutes of Health · National Institute of Biomedical Imaging and Bioengineering

PubMed
Indexed incrossrefpubmed

Abstract

Bioanalytical methods have experienced unprecedented growth in recent years, driven in large part by the need for faster, more sensitive, more portable ("point of care") systems to detect protein biomarkers for clinical diagnosis. Electrochemical detection strategies, used in conjunction with immunosensors, offer advantages because they are fast, simple, and low cost. Recent developments in electrochemical immunosensors have significantly improved the sensitivity needed to detect low concentrations of biomarkers present in early stages of cancer. Moreover, the coupling of electrochemical devices with nanomaterials, such as gold nanoparticles, carbon nanotubes, magnetic particles, and quantum dots, offers…

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